Foods are wonders.
Not because they look impressive, but because nature quietly designs them to heal, protect, and nourish us cell by cell, day after day.
Among these natural wonders is ABM Mushroom (Agaricus blazei Murill). Often called the “mushroom of life,” it has been treasured for generations not as a miracle cure, but as a gentle supporter of balance, resilience, and inner strength.
1. May help reduce inflammation
A two-year rat study has found that high doses of Agaricus blazei Murrill (ABM) were linked to longer lifespans, possibly due to reduced cancer rates. In humans, the extract reduced proinflammatory cytokines.
A different clinical study reported decreased inflammatory markers in individuals with ulcerative colitis and Crohn's disease after just 12 days of treatment.
These anti-inflammatory effects may also explain the mushroom's potential benefits in managing allergies, asthma, autoimmune diseases, and certain cancers.
2. May help relieve allergies
Studies in both mice and humans suggest that Agaricus blazei Murrill (ABM) extracts have strong antiallergic effects.
- In mouse models, ABM reduced allergic responses such as ear swelling and asthma symptoms. This effect was achieved by lowering IgE, IgG1, and bronchial eosinophil levels, and by promoting a more balanced Th1/Th2 response through the regulation of mast cell activity and T cell differentiation.
- In a human clinical trial, individuals with birch allergy and asthma who took ABM extract for two months before the pollen season experienced fewer allergy symptoms, reduced medication use, and lower IgE levels.
3. Protect against viral infections with ABM Mushroom
- In vitro, ABM fractions inhibited the viral effects of western equine encephalitis.
- In patients with chronic hepatitis C resistant to IF-a, oral ABM slightly reduced viral load and appeared to upregulate IFN-a receptor genes.
- These findings suggest that ABM's immune-stimulating properties may enhance the body's defense against viral infections.
4. Liver Function can improve with ABM Mushroom
- A one-year clinical observation suggests that Agaricus blazei Murrill (ABM) extract may help normalize liver function in patients with chronic hepatitis B.
- Among four patients studied, ABM supplementation led to a noticeable reduction in liver enzymes (AST and ALT), with three showing gradual improvement and one complex case improving after nine months.
- One patient also experienced symptom relief. Importantly, no side effects were reported, supporting ABM's safety as a supplement.
- Rich in B-glucans-compounds linked to anti-inflammatory and antiviral effects-ABM may also benefit individuals with type 2 diabetes and liver complications.
5. ABM Mushroom has strong Antioxidant Properties
- Research shows that Agaricus blazei Murrill (ABM) aqueous extracts can significantly reduce levels of reactive oxygen species (ROS) by interfering with ROS-producing enzymes and suppressing various reactive compounds.
- Evidence includes reduced superoxide anion formation, inhibition of neutrophil oxidative bursts, and decreased activity of oxidative enzymes like horseradish peroxidase (HRP) and myeloperoxidase (MPO).
- These antioxidant effects highlight ABM's strong potential as a pharmacological agent against oxidative stress and its promise as a valuable nutritional and pharmaceutical source of new therapeutic compounds.
6. ABM Mushroom can affect cytokine production
Agaricus blazei Murrill (ABM) extracts have shown notable effects on cytokine production, underscoring their potential in immune modulation.
7. Immune Modulation with ABM Mushroom
- Several studies have shown that Agaricus blazei Murrill (ABM) exerts antitumor effects through multiple mechanisms, including enhanced natural killer (NK) cell activity and the actions of B-glucans, which stimulate and regulate immune function.
- These immune-modulating effects may contribute to tumor regression and play a role in cancer prevention and treatment.
8. ABM Mushroom may help protect against Liver Cancer
- Polysaccharides from Agaricus blazei Murrill (ABM) can suppress the expression and activity of liver cytochrome P450 (CYP) enzymes, which play key roles in metabolizing xenobiotics and activating certain carcinogens.
- This suppression-likely mediated by cytokine release and modulation of the aryl hydrocarbon receptor (AHR) pathway-may reduce the formation of carcinogenic compounds and prolong the effectiveness of chemotherapy drugs by slowing their breakdown in the liver.
9. ABM Mushroom may help Kill Leukemia Cells
Researchers found that Agaricus blazei Murrill (ABM) can help kill leukemia cells (THP-1) by triggering a process called apoptosis, or programmed cell death.
- This happens through the buildup of reactive oxygen species, which activate a protein (mcJNK) in the mitochondria.
- The mushroom also reduces the activity of NF-kB, a protein that normally helps cells survive. By lowering NF-kB activity, ABM makes it easier for the cancer cells to die-similar to how some chemotherapy drugs work.
10. ABM Mushroom may help balance Immune responses
- Research suggests that Agaricus blazei Murrill (ABM) may help balance immune responses by shifting the Th1/Th2 profile toward Th1, thereby strengthening defenses against infections and possibly cancer.
- In Crohn's disease, which involves predominant Th1 and Th17 activity, ABM lowered levels of IL-2 (a Thi cytokine) and IL-17 (a Th17 cytokine).
- In ulcerative colitis-associated with a Th2-skewed immune profile-levels of Th2 cytokines IL-4 and IL-13 decreased after ABM intake.
- This immunomodulatory effect suggests that ABM may be beneficial in managing inflammatory and autoimmune-like disorders and might also have a role as an adjuvant in cancer vaccines.
11. ABM Mushroom may improve Quality of Life in Cancer Patients
- help maintain Natural Killer NK cell activity in gynecological cancer patients undergoing chemotherapy
- NK Cells are critical immune cells that recognize and destroy cancer cells
- Evidence suggests ABM may promote NK cell infiltration into tumors, enhance their ability to kill cancer cells, and trigger tumor cell death. In clinical settings,
- ABM extract intake during chemotherapy has been associated with improved quality of life, including better appetite, weight maintenance, increased physical strength, and reduced nausea, vomiting, and insomnia.
As a quality convenience,
We have E.EXCEL NUTRIACT / eLEAD E-MUNITY given to us to use on daily basis to nourish our immune system.
E.EXCEL NUTRIACT
Ingredients: Agaricus Blazei Murill (ABM), Lentinus edodes (Shiitake mushroom), Grifola frondosa (Maitake mushroom), Ganoderma lucidum (Ling Zhi)
eLEAD E-MUNITY
Ingredients: Cordyceps Mycelium, Shiitake mushroom, ABM mushroom, and Maitake mushroom, Cassia tora, Blueberries
for more info, welcome to contact me at +65- 9090 9942 .
Stay Healthy.
Best Regards,
Joselyne
Excellence Lifestyle Coach
+65-9090 9942
